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You're welcome ;-)
From Tokyo, some Shinkansen stop at Kyoto and some others to Osaka. But Shinkansen will arrive at shin-osaka, this station is not in town. So you will have to take another train to go downtown.
Another solution is to take a train to Kyoto, and then from Kyoto Station, another train to Osaka station.
You can plan all your train travels with http://www.hyperdia.com/en/ it's easy to use.
If you've got a lot of luggage, you can ask your hotel to send them with taqubin, it's not so expensive (about 1900 yens for a bit suitcase), so you can travel without carrying your luggage. And in Shinkansen there is not so many place for luggages.
Feel free to ask if you have any questions.