For your challenge: I doubt that better ways of observing something would mean a disadvantage (unless it narrows our scope down so much that we cannot see the whole picture somehow).
Nice article! Microbiology was my favorite class in my last semester. Those bugs are amazing. HGF is even more prevalent in biofilms and are curse (as you mentioned, antibiotic resistance) as well as potentially useful (living materials, nanorods for tech) and immensely important (biofilms in our intestines fighting off disease). Microbes are a topic that should get more attention. Germophodes really miss out. Cheers!