The Ketamine produces psychological dependence and long-term physical dependence.

It also produces short-term tolerance can produce serious and unpredictable effects and eventually produces irreversible brain effects.

It is important to take into account that there are several types of depression, which are: major depression, dysthymia, bipolar disorder and post-partum depression.

Depending on the problem, treatment for depression may be necessary in two ways: pharmacological and psychotherapy.