I think many creation/origin myths do examine or postulate the entrance of misery and conflict in this world. The "Fall" story in the three major monotheism (Judaism, Christianity, Islam) relate to man choosing to essentially reject the garden given. I think the Sumerians had a myth about the gods giving a choice of living in cities/civilization with the caveat that man also must accept war and inequality along with art, music, and luxuries. Even the Nietzchean sci-fi movie "Matrix" had man reject the paradise of the first AI simulation. Maybe misery is inherent in man's existence.