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RE: Fascinating Proteins #Aquaporins
Excellent article! I have a question, please.
Metabotropic receptor binds to ADH on the cell surface, signaling via the G-protein complex for more Aquaporines.
Does this mean that there aren't a set number of Aquaporines in a cell membrane? Can the acquaporines change to allow more or less water to go through them or are more acquaporines created when the ADH content is higher in the blood?
That is true, this will signal for more Aquaporines in the membranes. It actually triggers the full transcription chain making it more abundantly expressed, and it goes surprisingly fast. ADH receptor blocking can even be used to treat low blood salt, by decreasing water uptake to the cirkulation via this mechanism.
If i remember correctly :)
Thanks for reading, much appreciated, and good question!