The Man Who Was Facinated By The Beauty Of Chemical Reaction.

joblissby (40)in #science • 7 years ago (edited)

Alexander rudensky was born in 1949 by a jewish parent. His father was a junior officer which later became a senior office in the Russia army. During the Jewish purging, his father was dismissed. His father later studied engineering.

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His mother was 16 when the war started. Her family was evacuated from Moscow and ended up in the Ural Mountains, where my grandfather died and left grandmother and his mother and his uncle alone. The came back in 1944 to Moscow, where she later graduated from Moscow University Law School. That was in the early ‘50s, the time of the Doctors’ Plot, and not necessarily the best time for a young, Jewish woman to practice law. She ended up getting a second edu)cation and became a teacher of Russian literature.

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Science was greatly reHspected in the Soviet Union. grew up at the time where fascination with science was widespread, at least in the Soviet Union. He was not quite five years old when heard on the radio a report of the first space flight of Yuri Gagarin.

I remember the shift in fascination from astronomy to physics to biology, with some delay, among Soviet schoolchildren and the public at large.

Alexander Rudensky then enrolled in evening chemistry school at the Faculty of Chemistry of Moscow State University, and that was pretty amazing because graduate students and professors of the Faculty of Chemistry were teaching high schoolers in the evening.

I loved organic synthesis, loved all the amazing glassware that was involved in it. By the time I finished high school, I was starting to find chemistry a bit dry.

Mr Rudensky still an undergraduate in biochemistry studies at the university of Moscow got the opportunity of working in an immunology chemistry laboratory during his spare time.

In 1979 mr Rudensky joined the lab of one mr Vitalij Yulin at the gabrichevsky institute of epidomolgy and micro biology in Moscow which happens to be one of the best molecular immunology labs in Russia.

While he was in the Gabrichevsky institute of epidomology and laboratory, he discovered he was finding biochemistry a bit dry. Mr Rudensky was happy when Mr Vitalij asked him to study the biological function of white blood cell. T cell, which mediate the body defence against pathogens.

I was thrilled when Mr Vitalj asked me to T Cells.

Alexander Rudensky after earning his PhD worked in Mr Vitalij lab for many years. Working as a research scientist.

Mr Rudensky was able to travel to West Berlin for the first time, for the first time, presented his work at the international immunology congress just before the fall of the Berlin Wall.

Alexander Rudensky wrote to Johnway.

Charles Jonway was a renowned american immunologist whose work he greatly admired. Mr Rudensky did not expect an answer from Jonway. surprisingly, he was stunned when Charles Johnway asked him to join his lab at the university school of medicine in new heaven. That was how Mr Rudensky migrated from Russia to United State of America.

He spoke about johnway in one of his interview

Johnway was a man that conceive at least one new idea each day.

After finishing his postdoctoral work in Charlie's lab, alexander Rudensky accepted a position at the university of Washington in Seattle which had an illustrious immunology department.

I was very lucky to recruit a group of brrilliant students in Seattle for 16 years- until a year and a half ago when my lab was relocated to New York.

Focusing On Regulatory T Cells.

Mr Rudensky explained that lately, research had been focused on specific population of white blood cells called regulatory T cells which can repress immune system instead reaction to attacking infection or cancer.

We have found out that these cells are critical for keeping other white blood cells in check; in their absence, the immune system instead of attacking "intruders"-for example, a cell infected with a virus or bacteria strike against normal cells and tissues causing monstrous inflammatory response that can be fatal.

Mr Rudensky explained that the basic research their lab conducting is to ascertain how regulatory T cells are formed and how they function is likely to have widespread clinical application . potential therapies that act by boasting or targeting these cells are now being explored for auto immune diseases such as diabetes, and rheumatoid arthritis, ad well as for cancer. Most types of turmours are infiltrated by regulatory T Cells., which are believed to suppress the immune system stability to fight turmor.

Interdisplinary Research.

I encouraged my students it to feel locked into one particular displine but to get broad exposure to life sciences by engaging in Intrrdisplinary Research.

To me, science remains a unique profession which gives people the opportunity to earn support for and pursue their ideas, and having such intellectual freedom is a great privilege and

Specialty:

Immunology

Institution:

Chair, Immunology Program, Sloan-Kettering Institute

Other Title:

Note

Note

Notes

Immunological Tolerance, T Cell Differentiation and Function.