What is Noma disease?

in #medicine2 years ago

Noma disease, also known as cancrum oris, is a rare and severe gangrenous infection that affects the soft tissues of the face, particularly the mouth and cheeks. It primarily occurs in malnourished children living in extreme poverty, often in developing countries. The disease can progress rapidly, leading to severe disfigurement and even death if left untreated.

The exact cause of Noma is not well understood, but it is believed to be a result of a combination of factors, including poor oral hygiene, #malnutrition, and weakened immune systems. Bacterial infections, particularly those caused by Fusobacterium necrophorum and Prevotella intermedia, are thought to play a role in the development of the disease.

Early symptoms of Noma include painful ulcers in the mouth, swelling, and fever. As the disease progresses, the affected tissues become necrotic (dead), leading to the destruction of the facial structures, including the bones.

Treatment for Noma involves a combination of approaches, including antibiotics to control the infection, nutritional support to address malnutrition, and surgical intervention to remove necrotic tissue and reconstruct the affected areas. Early detection and treatment are crucial to improve the chances of survival and minimize disfigurement.