Metal nanoparticles are demonstrating promising antiviral activity against pathogenic surrogates and clinical isolates

in #medical3 years ago

"metal nanoparticles are demonstrating promising antiviral activity against pathogenic surrogates and clinical isolates."
https://pubmed.ncbi.nlm.nih.gov/33029761/

"Zinc promotes immune functions and helps people resist infectious diseases including diarrhea, pneumonia and malaria14,15,16. Zinc is also needed for healthy pregnancies14."
https://www.cdc.gov/nutrition/micronutrient-malnutrition/micronutrients/index.html

Zinc2+ ion inhibits SARS-CoV-2 main protease and viral replication in vitro
https://pubmed.ncbi.nlm.nih.gov/34514483/

"Heavy metals including gold and silver are antibacterial, but copper’s specific atomic makeup gives it extra killing power, Keevil says. Copper has a free electron in its outer orbital shell of electrons that easily takes part in oxidation-reduction reactions (which also makes the metal a good conductor). As a result, Schmidt says, it becomes a “molecular oxygen grenade.” Silver and gold don’t have the free electron, so they are less reactive."
https://www.smithsonianmag.com/science-nature/copper-virus-kill-180974655/

"Silver nanoparticles have mainly been studied for their antimicrobial potential against bacteria, but have also proven to be active against several types of viruses including human imunodeficiency virus, hepatitis B virus, herpes simplex virus, respiratory syncytial virus, and monkey pox virus. The use of metal nanoparticles provides an interesting opportunity for novel antiviral therapies. Since metals may attack a broad range of targets in the virus there is a lower possibility to develop resistance as compared to conventional antivirals."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264685/

"AuNPs-As likely inhibit viral infection by blocking viral particles directly, showing a potent virucidal effect."
https://pubmed.ncbi.nlm.nih.gov/31801280/

"CDER is charged with advancing public health through the review, regulation, and research of potential treatments."
https://www.fda.gov/drugs/news-events-human-drugs/studying-how-pathogens-cause-disease

"Operation Quack Hack leverages agency expertise and advanced analytics to protect consumers from fraudulent medical products"
https://www.fda.gov/news-events/fda-voices/fda-protects-patients-and-consumers-fraud-during-covid-19

"The FDA is particularly concerned that products that claim to cure, treat or prevent serious diseases like COVID-19 may cause consumers to delay or stop appropriate medical treatment, leading to serious and life-threatening harm."
https://www.fda.gov/news-events/press-announcements/coronavirus-update-fda-and-ftc-warn-seven-companies-selling-fraudulent-products-claim-treat-or

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