A Brief-history of Anti-Diabetic spectrum

in #blog7 years ago

1918: Early work with Guanidine (Synthlin use stopped In early 1920s) .

1922: First Exogenous Insulin administered to a Human.

1959: Metformin Introduced.

1983: First Recombinant Human Insulin.

1984: Second generation SUs.

2006: First DPP-4 inhibitor (Sitagliptin, Linagliptin).

2008: Colesevelam approved for Diabetes.

2009: Bromocriptine approved for Diabetes.

2013: First SGLT-2 inhibitor (Dapagliflozin). image

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